Adult, pediatric, and neonatal ventilation
The HAMILTON-C3 mechanical ventilator provides effective, safe, and lung-protective ventilation for adult, pediatric, and neonatal patients. For neonatal patients, a specifically developed neonatal proximal flow sensor is used. The tidal volume range goes down to as low as 2 ml.All features
INTELLiVENT-ASV is an advanced ventilation mode based on the Adaptive Support Ventilation (ASV) mode and acts as your assistant at the bedside. With this mode, the clinician sets target ranges for PetCO2 and SpO2, as well as limits for various controls. INTELLiVENT-ASV then adjust the controls for CO2 elimination (%MinVol) and oxygenation (PEEP and Oxygen), and keeps the patient within the predefined ranges with minimal clinician interaction.
INTELLiVENT-ASV continuously monitors specific physiologic parameters and adjusts the settings as appropriate, while always applying individualized lung-protective strategies.
When enabled, INTELLiVENT-ASV can also help promote early weaning with Quick Wean.
Clinical studies show that INTELLiVENT-ASV:
- Requires fewer manual adjustments than conventional ventilation, consequently reducing the workload for the healthcare team (1, 2, 3)
- Is rated as having the most technological capabilities of all evaluated modes in terms of safety, comfort, and weaning (4)
- Follows the latest recommendations for lung-protective ventilation in terms of tidal volumes and driving pressure (5, 6)
1. Arnal, J.M., et al., Closed loop ventilation mode in Intensive Care Unit: a randomized controlled clinical trial comparing the numbers of manual ventilator setting changes. Minerva Anestesiol, 2018. 84(1): p. 58-67.
2. Bialais E, Wittebole X, Vignaux L, Roeseler J, Wysocki M, Meyer J, Reychler G, Novotni D, Sottiaux T, Laterre PF, Hantson P. Minerva Anestesiol. Closed-loop ventilation mode (IntelliVent-ASV) in intensive care unit: a randomized trial of ventilation delivered. 2016 Jun;82(6):657-68.
3. Fot EV, Izotova NN, Yudina AS, Smetkin AA, Kuzkov VV, Kirov MY. Front Med (Lausanne). Automated weaning from mechanical ventilation after off-pump coronary artery bypass grafting. 2017 Mar 21;4:31.
4. Mireles-Cabodevila E., Hatipoğlu U., Chatburn RL. A Rational Framework for Selecting Modes of Ventilation. Respir Care. 2013 Feb;58(2):348- 66. *Erratum in: Respir Care. 2013 Apr;58(4):e51.
5. Arnal JM, Saoli M, Garnero A. Heart Lung. Airway and transpulmonary driving pressures and mechanical powers selected by INTELLiVENT-ASV in passive, mechanically ventilated ICU patients. 2020 Jul-Aug;49(4):427-434.
6. Arnal JM. Intensive Care Med Exp 2016, 4(Suppl 1):A602.Read more All features
Adaptive Support Ventilation (ASV)
All Hamilton Medical ventilators feature the intelligent ventilation mode, Adaptive Support Ventilation® (ASV®). ASV continuously adjusts respiratory rate, tidal volume, and inspiratory pressure depending on the patient’s lung mechanics and effort. ASV adapts ventilation breath-by-breath, 24 hours a day, from intubation to extubation.
A lung-protective strategy ensures ASV’s safety. ASV attempts to guide the patient using a favorable breathing pattern. ASV has been a well established mode in critical care since 1998 and has become a standard ventilation mode in many units around the world.
Clinical studies show that ASV:
- Shortens the duration of weaning without increasing the number of interventions by the clinician (1, 2, 3, 4 ,5)
- Shortens the duration of mechanical ventilation in various patient populations with fewer manual settings (3, 5, 6)
1. Campbell RS, Branson RD, Johannigman JA. Adaptive support ventilation. Adaptive support ventilation. Respir Care Clin N Am. 2001 Sep;7(3):425-40.
2. Celli P, Privato E, Ianni S, Babetto C, D'Arena C, Guglielmo N, Maldarelli F, Paglialunga G, Rossi M, Berloco PB, Ruberto F,Pugliese F. Adaptive Support Ventilation versus Synchronized Intermittent Mandatory Ventilation with Pressure Support in weaning patients after orthotopic liver transplantation. Transplant Proc. 2014 Aug 20. [Epub ahead of print]
3. Kirakli C, Naz I, Ediboglu O, Tatar D, Budak A, Tellioglu E. Chest. A randomized controlled trial comparing the ventilation duration between Adaptive Support Ventilation and Pressure Assist/Control Ventilation in medical ICU patients. 2015 Jun;147(6):1503-9.
4. Kirakli C, Ozdemir I, Ucar ZZ, Cimen P, Kepil S, Ozkan SA. Adaptive support ventilation for faster weaning in COPD: a randomised controlled trial. Eur Respir J. 2011 Oct;38(4):774-80.
5. Tam MK, Wong WT, Gomersall CD, Tian Q, Ng SK, Leung CC, Underwood MJ. A randomized controlled trial of 2 protocols for weaning cardiac surgical patients receiving adaptive support ventilation. J Crit Care. 2016 Jun;33:163-8.
6. Zhu F, Gomersall CD, Ng SK, Underwood MJ, Lee A. A randomized controlled trial of adaptive support ventilation mode to wean patients after fast-track cardiac valvular surgery Anesthesiology. 2015 Apr;122(4):832-40.Read more All features
P/V Tool® Pro - the protective ventilation tool
The Protective Ventilation Tool (P/V Tool Pro) performs a respiratory mechanics maneuver that records a quasi-static pressure/volume curve. This method can be used to assess lung recruitability and determine the recruitment strategy to apply.
The P/V Tool Pro can also be used to perform a sustained inflation recruitment maneuver and measure the increase in lung volume. It is particularly helpful for ARDS patients, as selecting an appropriate lung recruitment strategy and the correct PEEP setting as an anti-derecruiting force are critical for this patient group.
In combination with esophageal pressure measurement, the P/V Tool Pro can give you a clearer understanding of the lung and chest-wall mechanics. This enables you to apply a lung-protective ventilation strategy by titrating the PEEP level (Talmor 2008), and optimizing the parameters for the recruitment maneuver, driving pressure and tidal volume.All features
High-performance noninvasive ventilation (NIV)
The noninvasive ventilation modes deliver pressure-supported, flow-cycled spontaneous breaths (NIV and NIV-ST mode) and pressure-controlled, time-cycled mandatory breaths (NIV-ST mode). In NIV modes, the ventilator functions as a demand-flow system. When pressure support in NIV mode is set to zero, the ventilator functions like a conventional CPAP system.
Compared to a compressed-air-based intensive care ventilator, this ventilator provides a higher peak flow rate of over 240 l/min due to an integrated high-performance turbine. This guarantees optimal performance even with large leaks. In addition, the leak compensation function adapts to changing breath patterns and airway leaks to achieve optimum synchronization between patient and device.All features
High flow oxygen therapy
The HAMILTON-C3 optionally provides an integrated high flow oxygen therapy* mode. With this enhancement, the HAMILTON-C3 gives you a variety of therapy options in one device, including invasive and noninvasive ventilation, and high flow oxygen therapy. In just a few steps, you can change the interface and use the same device and breathing circuit to accommodate your patient’s needs.
*Always use active humidification during high flow oxygen therapy.All features
Mobility for intra-hospital transport
The high-performance turbine enables the HAMILTON-C3 mechanical ventilator to be completely independent from compressed air, and its integrated high-capacity battery allows you to ventilate your patients during intrahospital transport without the need for an external power source. The compact design of the HAMILTON-C3 mechanical ventilator makes handling much easier.All features
Integrated high-performance turbine
The integrated high-performance turbine enables the HAMILTON-C3 to be completely independent from compressed air. This reduces weight and saves space.All features
On-screen help for alarm troubleshooting
The HAMILTON-C3 helps troubleshooting with an integrated on-screen help system. Whenever there is a problem, the HAMILTON-C3 not only generates an alarm using the alarm lamp, sound, and message bar on the display, but also helps you identify where the problem is. As a result, you can immediately start with the troubleshooting.All features
The nCPAP modes are designed so that you only need to set the desired CPAP pressure. The flow is subsequently adjusted based on patient conditions and potential leaks. This prevents unintended peak pressures, guarantees highly efficient leak compensation, and helps to reduce oxygen consumption. Flow adjustment occurs very rapidly due to high sensitivity of the pressure measurement.All features
Tube Resistance Compensation (TRC)
To reduce the patient’s work of breathing, the ventilator’s tube resistance compensation (TRC) feature offsets the flow resistance imposed by the tracheal (ET) or tracheostomy tube.All features
Configurable loops and trends
The ventilator can display a dynamic loop based on two selectable monitored parameters. With the trend function, the ventilator can display monitored parameters in a selectable time frame. The device continually stores the monitored parameters in memory, so you have access to any of this data, even in standby.All features
Dynamic Lung for simplified patient monitoring
The Dynamic Lung panel is part of the Ventilation Cockpit. It displays tidal volume, lung compliance, interaction with the heart, patient triggering, and resistance in real-time. The lungs expand and contract in synchrony with actual breaths. The shape of the lungs changes with compliance. Numeric values for resistance (Rinsp) and compliance (Cstat) are also displayed.All features
Vent Status for weaning assessment
The Vent Status panel is part of the Ventilation Cockpit. It displays six parameters related to the patient’s ventilator dependence, including oxygenation, CO2 elimination, and patient activity. A floating indicator (floater) that moves up and down within the column shows the value for a given parameter. The panel is updated breath by breath. When all values are in the weaning zone, the Vent Status panel is framed in green, indicating that spontaneous breathing trials should be considered.All features
Hot-swappable battery backup
A battery operating time of more than 7 hours is provided by one integrated and one hot-swappable battery. The battery operating time can be prolonged indefinitely with the use of additional hot-swappable batteries.All features
Optimal alarm detection
Even from a distance or at high noise levels, the HAMILTON-C3 mechanical ventilator alarming is easily identified by the top-mounted 360°-visible alarm lamp. The optional nurse call capability provides additional support for optimal alarm detection.All features
Integrated pneumatic nebulizer
The integrated pneumatic nebulizer is fully synchronized with the inspiration and exhalation timing. The delivery of a fine mist of drug aerosol particles helps you improve your ventilation efficiency, for example in cases of bronchospasm or chronic hypercapnia.All features
Serial interface for connection to PDMS or patient monitors
The serial RS-232 interface provides ports for connection to hospital monitors or Patient Data Management Systems (PDMS).All features
All ventilation modes
The ventilator supports the following types of modes:
- Intelligent ventilation modes with Adaptive Support Ventilation (ASV) and INTELLiVENT-ASV
- Pressure-controlled modes (including biphasic modes)
- Adaptive volume-controlled modes
- Conventional volume-controlled modes
- Pressure support modes
- Modes for noninvasive ventilation
- High flow oxygen therapy
Thanks to its biphasic pneumatic design, the ventilator always yields to spontaneous breathing in all modes. This is achieved through a special valve control system independent of any trigger mechanism.All features
Leak compensation for NIV and invasive ventilation
The leak compensation function automatically adjusts the inspiratory and expiratory trigger sensitivity to airway leaks, and ensures optimal synchronization with the patient’s breathing pattern. This is achieved in both invasively and noninvasively ventilated patients.All features
Proximal flow sensor for precise measurements
The proximal flow sensor precisely measures the pressure, volume, and flow directly at the patient’s airway opening. This provides the required sensitivity and response time, and prevents dead space ventilation. Your patient is better synchronized and has less work of breathing as a result.All features
Depending on your country, some features may be available as options, may have different specifications than described on this website, or may not be available. Contact your Hamilton Medical representative for details.