• Adult, pediatric, and neonatal ventilation

    The HAMILTON-C1 mechanical ventilator provides effective, safe, and lung-protective ventilation for adult, pediatric, and neonatal patients. For neonatal patients, a specifically developed neonatal proximal flow sensor is used. The tidal volume range goes down to as low as 2 ml.

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  • Integrated high-performance turbine

    The integrated high-performance turbine enables the HAMILTON-C1 to be completely independent from compressed air. This reduces weight and saves space.

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    INTELLiVENT-ASV is an advanced ventilation mode based on the Adaptive Support Ventilation (ASV) mode and acts as your assistant at the bedside. With this mode, the clinician sets target ranges for PetCO2 and SpO2, as well as limits for various controls. INTELLiVENT-ASV then adjust the controls for CO2 elimination (%MinVol) and oxygenation (PEEP and Oxygen), and keeps the patient within the predefined ranges with minimal clinician interaction.

    INTELLiVENT-ASV continuously monitors specific physiologic parameters and adjusts the settings as appropriate, while always applying individualized lung-protective strategies.

    When enabled, INTELLiVENT-ASV can also help promote early weaning with Quick Wean. 

    Clinical studies show that INTELLiVENT-ASV:

    • Requires fewer manual adjustments than conventional ventilation, consequently reducing the workload for the healthcare team
      (1, 2, 3)
    • Is rated as having the most technological capabilities of all evaluated modes in terms of safety, comfort, and weaning (4)
    • Follows the latest recommendations for lung-protective ventilation in terms of tidal volumes and driving pressure (5, 6)


    1. Arnal, J.M., et al., Closed loop ventilation mode in Intensive Care Unit: a randomized controlled clinical trial comparing the numbers of manual ventilator setting changes. Minerva Anestesiol, 2018. 84(1): p. 58-67.

    2. Bialais E, Wittebole X, Vignaux L, Roeseler J, Wysocki M, Meyer J, Reychler G, Novotni D, Sottiaux T, Laterre PF, Hantson P. Minerva Anestesiol. Closed-loop ventilation mode (IntelliVent-ASV) in intensive care unit: a randomized trial of ventilation delivered. 2016 Jun;82(6):657-68.

    3. Fot EV, Izotova NN, Yudina AS, Smetkin AA, Kuzkov VV, Kirov MY. Front Med (Lausanne). Automated weaning from mechanical ventilation after off-pump coronary artery bypass grafting. 2017 Mar 21;4:31.

    4. Mireles-Cabodevila E., Hatipoğlu U., Chatburn RL. A Rational Framework for Selecting Modes of Ventilation. Respir Care. 2013 Feb;58(2):348- 66. *Erratum in: Respir Care. 2013 Apr;58(4):e51.

    5. Arnal JM, Saoli M, Garnero A. Heart Lung. Airway and transpulmonary driving pressures and mechanical powers selected by INTELLiVENT-ASV in passive, mechanically ventilated ICU patients. 2020 Jul-Aug;49(4):427-434.

    6. Arnal JM. Intensive Care Med Exp 2016, 4(Suppl 1):A602.

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  • High-performance noninvasive ventilation (NIV)

    The noninvasive ventilation modes deliver pressure-supported, flow-cycled spontaneous breaths (NIV and NIV-ST mode) and pressure-controlled, time-cycled mandatory breaths (NIV-ST). In NIV modes, the ventilator functions as a demand-flow system. When pressure support in NIV mode is set to zero, the ventilator functions like a conventional CPAP system.

    Compared to a compressed-air-based intensive care ventilator, the HAMILTON-C1 ventilator provides a higher peak flow rate of up to 260 l/min due to an integrated high-performance turbine. This guarantees optimal performance even with large leaks. In addition, the leak compensation function adapts to changing breath patterns and airway leaks to achieve optimum synchronization between patient and device. 

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  • High flow oxygen therapy

    The HAMILTON-C1 optionally provides an integrated high flow oxygen therapy* mode. With this enhancement, the HAMILTON-C1 gives you a variety of therapy options in one device, including invasive and noninvasive ventilation, and high flow oxygen therapy. In just a few steps, you can change the interface and use the same device and breathing circuit to accommodate your patient’s needs.

    *Always use active humidification during high flow oxygen therapy.

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  • Hamilton Connect Module

    The Hamilton Connect Module provides wireless and wired connectivity protected by state-of-the-art security. It also enables connection with the Hamilton Connect App.


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  • Hamilton Connect App

    Built to meet the needs of modern healthcare providers, the Hamilton Connect App* gives you access to respiratory data. It also provides you with tools designed to facilitate and streamline your ventilation workflow. All you need is a mobile device and a Hamilton Medical ventilator with the Hamilton Connect Module.

    *The Hamilton Connect App is not intended to replace the real-time display of data on the ventilator. DO NOT USE the app to supplement or replace any part of the hospital's device monitoring.

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  • Mobility for intra-hospital transport

    The high-performance turbine enables the HAMILTON-C1 mechanical ventilator to be completely independent from compressed air, and its integrated high-capacity battery allows you to ventilate your patients during intrahospital transport without the need for an external power source. The compact design of the HAMILTON-C1 mechanical ventilator makes handling much easier.

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  • Speaking valve

    The Speak Valve option gives tracheostomized patients a voice, and allows them to swallow even while receiving respiratory support from the ventilator. In pressure-controlled modes (PCV+, SPONT, PSIMV+), an optional feature enables use of conventional speaking valves with the HAMILTON-C1. Monitoring, triggering, and alarm management have been adjusted to allow the use of speaking valves. 

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  • Adaptive Support Ventilation (ASV)

    All Hamilton Medical ventilators feature the intelligent ventilation mode, Adaptive Support Ventilation® (ASV®). ASV continuously adjusts respiratory rate, tidal volume, and inspiratory pressure depending on the patient’s lung mechanics and effort. ASV adapts ventilation breath-by-breath, 24 hours a day, from intubation to extubation.

    A lung-protective strategy ensures ASV’s safety. ASV attempts to guide the patient using a favorable breathing pattern. ASV has been a well established mode in critical care since 1998 and has become a standard ventilation mode in many units around the world.

    Clinical studies show that ASV:

    • Shortens the duration of weaning without increasing the number of interventions by the clinician (1, 2, 3, 4 ,5)
    • Shortens the duration of mechanical ventilation in various patient populations with fewer manual settings (3, 5, 6)


    1. Campbell RS, Branson RD, Johannigman JA. Adaptive support ventilation. Adaptive support ventilation. Respir Care Clin N Am. 2001 Sep;7(3):425-40.

    2. Celli P, Privato E, Ianni S, Babetto C, D'Arena C, Guglielmo N, Maldarelli F, Paglialunga G, Rossi M, Berloco PB, Ruberto F,Pugliese F. Adaptive Support Ventilation versus Synchronized Intermittent Mandatory Ventilation with Pressure Support in weaning patients after orthotopic liver transplantation.  Transplant Proc. 2014 Aug 20. [Epub ahead of print]

    3. Kirakli C, Naz I, Ediboglu O, Tatar D, Budak A, Tellioglu E. Chest. A randomized controlled trial comparing the ventilation duration between Adaptive Support Ventilation and Pressure Assist/Control Ventilation in medical ICU patients. 2015 Jun;147(6):1503-9.

    4. Kirakli C, Ozdemir I, Ucar ZZ, Cimen P, Kepil S, Ozkan SA. Adaptive support ventilation for faster weaning in COPD: a randomised controlled trial. Eur Respir J. 2011 Oct;38(4):774-80.

    5. Tam MK, Wong WT, Gomersall CD, Tian Q, Ng SK, Leung CC, Underwood MJ. A randomized controlled trial of 2 protocols for weaning cardiac surgical patients receiving adaptive support ventilation.  J Crit Care. 2016 Jun;33:163-8.

    6. Zhu F, Gomersall CD, Ng SK, Underwood MJ, Lee A. A randomized controlled trial of adaptive support ventilation mode to wean patients after fast-track cardiac valvular surgery Anesthesiology. 2015 Apr;122(4):832-40.

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  • CPR ventilation

    CPR ventilation adapts ventilation settings to situations where CPR is being performed. It supports the CPR workflow with quick access to preconfigurable settings, adequate alarm and trigger adjustment, and CPR-timer display. The main monitoring parameters and curves relevant to CPR ventilation are also displayed.

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  • Volumetric capnography

    Proximal flow and CO2 measurement enables Hamilton Medical ventilators to perform up-to-date volumetric capnography, which provides an important basis for the assessment of ventilation quality and metabolic activity.

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  • SpO2 measurement

    The integration of the SpO2 option with Hamilton Medical ventilators offers an innovative solution for noninvasive measurement. Hamilton Medical also provides a comprehensive portfolio of SpO2 sensors.

    More information

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  • nCPAP modes

    The nCPAP modes are designed so that you only need to set the desired CPAP pressure. The flow is subsequently adjusted based on patient conditions and potential leaks. This prevents unintended peak pressures, guarantees highly efficient leak compensation, and helps to reduce oxygen consumption. Flow adjustment occurs very rapidly due to high sensitivity of the pressure measurement.

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  • All ventilation modes

    The ventilator supports the following types of modes:

    • Intelligent ventilation modes with Adaptive Support Ventilation (ASV) and INTELLiVENT-ASV
    • Pressure-controlled modes (including biphasic modes)
    • Volume-controlled modes (adaptive)
    • Pressure support modes
    • Modes for noninvasive ventilation
    • High flow oxygen therapy
    • Volume support mode
    • CPR ventilation

    Thanks to its biphasic pneumatic design, the ventilator always yields to spontaneous breathing in all modes. This is achieved through a special valve control system independent of any trigger mechanism. 

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  • Leak compensation for NIV and invasive ventilation

    The leak compensation function automatically adjusts the inspiratory and expiratory trigger sensitivity to airway leaks, and ensures optimal synchronization with the patient’s breathing pattern. This is achieved in both invasively and noninvasively ventilated patients.

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  • Vent Status for weaning assessment

    The Vent Status panel is part of the Ventilation Cockpit. It displays six parameters related to the patient’s ventilator dependence, including oxygenation, CO2 elimination, and patient activity. A floating indicator (floater) that moves up and down within the column shows the value for a given parameter. The panel is updated breath by breath. When all values are in the weaning zone, the Vent Status panel is framed in green and displays a timer, indicating that spontaneous breathing trials should be considered. 

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  • Dynamic Lung for simplified patient monitoring

    The Dynamic Lung panel is part of the Ventilation Cockpit. It displays tidal volume, lung compliance, interaction with the heart, patient triggering, and resistance in real-time. The lungs expand and contract in synchrony with actual breaths. The shape of the lungs changes with compliance. Numeric values for resistance (Rinsp) and compliance (Cstat) are also displayed.

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  • Proximal flow sensor for precise measurements

    The proximal flow sensor precisely measures the pressure, volume, and flow directly at the patient’s airway opening. This provides the required sensitivity and response time, and prevents dead space ventilation. Your patient is better synchronized and has less work of breathing as a result. 

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  • Configurable loops and trends

    The ventilator can display a dynamic loop based on two selectable monitored parameters. With the trend function, the ventilator can display monitored parameters in a selectable time frame. The device continually stores the monitored parameters in memory, so you have access to any of this data, even in standby. 

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  • Optimal alarm detection

    Even from a distance or at high noise levels, the HAMILTON-C1 mechanical ventilator alarming is easily identified by the top-mounted 360°-visible alarm lamp. The optional nurse call capability provides additional support for optimal alarm detection.

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  • Integrated pneumatic nebulizer

    The integrated pneumatic nebulizer is fully synchronized with the inspiration and exhalation timing. The delivery of a fine mist of drug aerosol particles helps you improve your ventilation efficiency, for example in cases of bronchospasm or chronic hypercapnia.

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  • Serial interface for connection to PDMS or patient monitors

    The serial RS-232 interface provides ports for connection to hospital monitors or Patient Data Management Systems (PDMS).

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  • Remote access to humidifier controls and status

    The unique ventilator connectivity option allows control of the HAMILTON-H900 humidifier from the ventilator. All controls, monitoring parameters, and alarms are available and can be controlled from the ventilator. The humidifier can also automatically select the humidification mode (invasive, noninvasive and high flow) based on the selected ventilation mode.

    This feature is not available in all markets.

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Important note

Depending on your country, some features may be available as options, may have different specifications than described on this website, or may not be available. Contact your Hamilton Medical representative for details.