Spontaneous breathing trial (SBT) in ASV mode

Author: Jean-Michel Arnal, Simon Franz, Reviewer: Matthias Himmelstoss, Sebastian Hollenberg, Thomas Reimer, Bernhard Schmitt

How can I perform a spontaneous breathing trial when my patient is being ventilated with ASV®?

Spontaneous breathing trials (SBTs) are among the most commonly used techniques to facilitate weaning from mechanical ventilation. Conducting the initial SBT with pressure augmentation was more likely to be successful, produced a higher rate of extubation success and was associated with a trend towards lower ICU mortality when compared with the T-piece SBT (1).

If your patient is on ASV, you can perform a pressure-support SBT as follows. Firstly, decrease PEEP to 5 cmH2O and lower the target minute volume (%MinVol) setting to reduce the pressure support as needed. If the pressure support on the current %MinVol setting is higher than 15 cmH2O, the %MinVol setting can be lowered first to 70%, and then to 25% to gradually reduce the level of pressure support down to 5-8 cmH2O for the SBT. 

The patient should be monitored both clinically and using the Vent Status panel. Clinical monitoring includes neurological status, effort to breathe, heart rate, and blood pressure. 

Respiratory monitoring includes SpO2, PetCO2, respiratory rate, and tidal volume. Patient exhaustion may lead to an increase in the respiratory rate with a small tidal volume, and cause an increase in pressure support according to the ASV algorithm.

If the patient remains stable for 30 minutes, you can consider extubation (2).

Relevant devices: all


  1. Schmidt, G. A., Girard, T. D., Kress, J. P., Morris, P. E., Ouellette, D. R., Alhazzani, W., . . . Truwit, J. D. (2016). Official Executive Summary of an American Thoracic Society/American College of Chest Physicians Clinical Practice Guideline: Liberation from Mechanical Ventilation in Critically Ill Adults. American Journal of Respiratory and Critical Care Medicine, 195(1), 115-119.
  2. Boles, J.-M., Bion, J., Connors, A., Herridge, M., Marsh, B., Melot, C., . . . Welte, T. (2007). Weaning from mechanical ventilation. European Respiratory Journal, 29(5), 1033-1056. 


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ASV, SBT, weaning, pressure support, MInVol, breathing rate, spontaneous

Date of Printing: 30.06.2022
The content of this Knowledge Base is intended for use by Hamilton Medical distribution partners for informational purposes only, and should not be copied, distributed or published in any way. While the information contained herein is believed to be accurate, it does not represent an official recommendation from Hamilton Medical AG, nor may it substitute an opinion, assessment or instructions provided by a trained healthcare professional.
Date of Printing: 30.06.2022
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