Predictive factors for successful use of INTELLiVENT®-ASV®


A study carried out in Japan reported on three years of experience with INTELLiVENT-ASV in ICU patients and looked at factors predicting successful use of this mode.

The authors of this single-center, retrospective observational study investigated the long-term success of INTELLiVENT-ASV and determined which factors might be predictors of its successful use. Patients were categorized into the success or failure group depending on whether they could be ventilated primarily in INTELLiVENT-ASV mode. The study protocol allowed for brief phases in another mode (e.g., change to PSV mode for manual spontaneous breathing trial) with a return to INTELLiVENT-ASV as soon as possible. Of the 189 patients ventilated with a HAMILTON-G5 ventilator, 71.4% were categorized into the success group, which included more than 90% of the patients with post-elective surgery.

Other findings included the following:

  • APACHE II score (cut-off value 24) was an independent predictive factor of successful INTELLiVENT-ASV
  • Reasons for needing to use another mode were strong inspiratory drive (requiring more than 200% MinVol) and asynchrony related to under-sedation during high inspiratory flows
  • Duration of mechanical ventilation, length of ICU stay, the need for ventilation after the ICU, and ICU mortality were all significantly lower in the success group

In their discussion, the authors also mentioned that the automation means INTELLiVENT-ASV can be expected to reduce the burdens on medical staff in comparison to other conventional ventilation methods. Therefore, it may be a better choice for the majority of mechanically ventilated patients.

Read the full publication

Katayama S, Tonai K, Shima J, Koyama K, Nunomiya S. Predictive factors for successful INTELLiVENT-ASV® use: a retrospective observational study. BMC Anesthesiol. 2020;20(1):94. Published 2020 Apr 25. doi:10.1186/s12871-020-01014-w

Date of Printing: 12.05.2021
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