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Ventilation for the smallest. Neonatal ventilator for the NICU and beyond

Neonatal ventilation. Available on all our ventilators

All Hamilton Medical ventilators – from high-end to transport devices – offer the option of noninvasive and invasive ventilation, with conventional and advanced ventilation modes for even the smallest patients.

Neonatal patient on a ventilator intubated and with a flow sensor Neonatal patient on a ventilator intubated and with a flow sensor

Precision is vital. Proximal flow measurements

The proximal flow sensor and expiratory valve enable the precise measurement of pressure and flow directly at the airway opening, ensuring the required sensitivity and a quick response time.

Neonatal patient with HFNC and mother

Careful, not too much! Tidal volumes as low as 2 ml

With the neonatal option, our devices provide tidal volumes as low as 2 ml for effective, safe, and lung-protective ventilation for neonates (Wheeler K, Klingenberg C, McCallion N, Morley CJ, Davis PG. Volume-targeted versus pressure-limited ventilation in the neonate. Cochrane Database Syst Rev. 2010;(11):CD003666. Published 2010 Nov 10. doi:10.1002/14651858.CD003666.pub31​).

Designed for neonates. Demand-flow nCPAP modes

The nCPAP modes are designed in such a way that you only need to set the desired CPAP/PEEP. The flow is subsequently adjusted automatically based on the patient need (demand flow) and variation in leakage, which prevents unintended peak pressures or loss of CPAP/PEEP, and guarantees leak compensation.

Trisha Degoyer Bimari Treuren Kathy Lira

Testimonios de clientes

Poder utilizar nCPAP con el HAMILTON‑T1 supone un avance increíble para nosotros. Ya no tenemos que intubar a ciertos bebés tan solo para su traslado.

Trisha Degoyer

Enfermera de Neumología para Neonatos en Life Flight
Intermountain Life Flight, Salt Lake City, Utah, EE. UU.

Testimonios de clientes

El HAMILTON‑G5 nos ha proporcionado múltiples opciones y funciones distintas, todas ellas muy necesarias en la UCI neonatal.

Bimari Treuren

Supervisora médica de terapia respiratoria
Florida Hospital for Children, Orlando (FL), EE. UU.

Testimonios de clientes

El HAMILTON-C3 es un respirador completamente portátil. Los pacientes en estado más delicado que ingresan en un área quirúrgica pueden seguir usando el mismo respirador durante todo el proceso de tratamiento.

Kathy Lira

Coordinadora de formación en pediatría y con pacientes neonatos
University Medical Center, Lubbock (TX), EE. UU.

Consumables and accessories specifically designed for neonates


Get in touch! We find the right solution for you

Book a free personal demonstration with one of our specialists to explore the benefits of our NICU ventilators further. They can guide you through the features, functionalities, and suitability of our devices based on your specific needs.

Alternatively, you can schedule a callback, and our team will reach out to provide you with the necessary information and assistance.

Volume-targeted versus pressure-limited ventilation in the neonate.

Wheeler K, Klingenberg C, McCallion N, Morley CJ, Davis PG. Volume-targeted versus pressure-limited ventilation in the neonate. Cochrane Database Syst Rev. 2010;(11):CD003666. Published 2010 Nov 10. doi:10.1002/14651858.CD003666.pub3


Damage caused by lung overdistension (volutrauma) has been implicated in the development bronchopulmonary dysplasia (BPD). Modern neonatal ventilation modes can target a set tidal volume as an alternative to traditional pressure-limited ventilation using a fixed inflation pressure. Volume targeting aims to produce a more stable tidal volume in order to reduce lung damage and stabilise pCO(2)


To determine whether volume-targeted ventilation (VTV) compared with pressure-limited ventilation (PLV) leads to reduced rates of death and BPD in newborn infants. Secondary objectives were to determine whether use of VTV affected outcomes including air leak, cranial ultrasound findings and neurodevelopment.


The search strategy comprised searches of the Cochrane Central Register of Controlled Trials, MEDLINE PubMed 1966 to January 2010, and hand searches of reference lists of relevant articles and conference proceedings.


All randomised and quasi-randomised trials comparing the use of volume-targeted versus pressure-limited ventilation in infants of less than 28 days corrected age.


Two review authors assessed the methodological quality of eligible trials and extracted data independently. When appropriate, meta-analysis was conducted to provide a pooled estimate of effect. For categorical data the relative risk (RR) and risk difference (RD) were calculated with 95% confidence intervals. Number needed to treat was calculated when RD was statistically significant. Continuous data were analysed using weighted mean difference.


Twelve randomised trials met our inclusion criteria; nine parallel trials (629 infants) and three crossover trials (64 infants).The use of VTV modes resulted in a reduction in the combined outcome of death or bronchopulmonary dysplasia [typical RR 0.73 (95% CI 0.57 to 0.93), NNT8 (95% CI 5 to 33)]. VTV modes also resulted in reductions in pneumothorax [typical RR 0.46 (95% CI 0.25 to 0.84), NNT 17 (95% CI 10 to 100)], days of ventilation [MD -2.36 (95% CI -3.9 to -0.8)], hypocarbia [typical RR 0.56 (95%CI 0.33 to 0.96), NNT 4 (95% CI 2 to 25)] and the combined outcome of periventricular leukomalacia or grade 3-4 intraventricular haemorrhage [typical RR 0.48 (95% CI 0.28 to 0.84), NNT 11 (95% CI 7 to 50)].


Infants ventilated using VTV modes had reduced death and chronic lung disease compared with infants ventilated using PLV modes. Further studies are needed to identify whether VTV modes improve neurodevelopmental outcomes and to compare and refine VTV strategies.