Noninvasive ventilation.

Your first line of defense

Immediate, effective, patient-centered. NIV during transport

Providing prompt and effective respiratory support is crucial. Noninvasive ventilation (NIV) is a valuable tool that enables you to manage acute respiratory distress without needing to intubate.

The benefits of noninvasive ventilation in prehospital care

Rapid deployment

NIV can be initiated quickly in the field, providing immediate relief to patients in respiratory distress by improving oxygenation and ventilation (Roessler MS, Schmid DS, Michels P, et al. Early out-of-hospital non-invasive ventilation is superior to standard medical treatment in patients with acute respiratory failure: a pilot study. Emerg Med J. 2012;29(5):409-414. doi:10.1136/emj.2010.1063931).

Reduced intubation rates

Early application of NIV has been shown to decrease the need for intubation, thereby reducing associated risks and improving patient outcomes (Farmer MJS, Callahan CD, Hughes AM, Riska KL, Hill NS. Applying Noninvasive Ventilation in Treatment of Acute Exacerbation of COPD Using Evidence-Based Interprofessional Clinical Practice. Chest. 2024;165(6):1469-1480. doi:10.1016/j.chest.2024.02.0402).

Improved patient comfort

By avoiding invasive airway management, NIV enhances patient comfort and co-operation during transport (Criner GJ, Gayen S, Zantah M, et al. Clinical review of non-invasive ventilation. Eur Respir J. 2024;64(5):2400396. Published 2024 Nov 7. doi:10.1183/13993003.00396-20243).

Enhanced safety profile

Using NIV in appropriate cases can lead to fewer complications, such as ventilator-associated pneumonia and shorter hospital stays (Criner GJ, Gayen S, Zantah M, et al. Clinical review of non-invasive ventilation. Eur Respir J. 2024;64(5):2400396. Published 2024 Nov 7. doi:10.1183/13993003.00396-20243).

When to use it. Clinical applications in prehospital care

COPD (Chronic obstructive pulmonary diseaseA) exacerbations: NIV is effective in managing acute exacerbations of COPD, improving the patient's gas exchange and reducing the work of breathing (Osadnik CR, Tee VS, Carson-Chahhoud KV, Picot J, Wedzicha JA, Smith BJ. Non-invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2017;7(7):CD004104. Published 2017 Jul 13. doi:10.1002/14651858.CD004104.pub44).
Cardiogenic pulmonary edema: In patients with acute pulmonary edema, NIV can decrease the pre- and afterload, thus improving cardiac output and respiratory function (Petrosyan H, Ghrmajyan H, Iskandaryan N, Tsaturyan A, Torozyan SH, Hayrapetyan H. Clinical effectiveness of non-invasive ventilation in patients with acute cardiogenic pulmonary edema. Eur Heart J Acute Cardiovasc Care. 2025 Apr;14(Suppl 1):zuaf044.037. doi: 10.1093/ehjacc/zuaf044.0375).
Acute hypoxemic respiratory failure: NIV can be used to manage various causes of hypoxemic respiratory failure, providing critical support during transport to definitive care (Munshi L, Mancebo J, Brochard LJ. Noninvasive Respiratory Support for Adults with Acute Respiratory Failure. N Engl J Med. 2022;387(18):1688-1698. doi:10.1056/NEJMra22045566).
Acute severe asthma: Early NIV can support safer prehospital stabilization by reducing the work of breathing, improving ventilation, and lowering the risk of intubation in severe asthma exacerbations (Soroksky A, Stav D, Shpirer I. A pilot prospective, randomized, placebo-controlled trial of bilevel positive airway pressure in acute asthmatic attack. Chest. 2003;123(4):1018-1025. doi:10.1378/chest.123.4.10187).

Availability

Noninvasive ventilation is available as an optional ventilation mode on the HAMILTON-T1 and HAMILTON-EM7.

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Noninvasive ventilation.

Your first line of defense

Immediate, effective, patient-centered. NIV during transport